EMERSE was used to identify 49 patients "diagnosed with HSCR [Hirschsprung's disease] from June 2010 to June 2020 who underwent a biopsy and definitive ERPT [endorectal pull‐through]." Finding: "inflammation on diagnostic rectal biopsy for HSCR is associated with increased anastomotic leak rates." @LotakisMD @NateRubalcava @ElizabethSpeck https://doi.org/10.1002/jpn3.12047

"Potentially eligible patients were identified through a text-search for the words 'myoclonus,' 'EEG,' 'SSEP,' and associated synonyms using...EMERSE" in study with findings that "SSEPs may retain prognostic value in patients with post-anoxic myoclonus." @wesleytkerr https://doi.org/10.1177/08850666241287154

EMERSE was used to identify gastrointestinal irAEs [immune-related adverse events] in patients with cancer treated with immune checkpoint inhibitors (ICIs), in a paper which "adds novel information to the current understanding of multisystem irAEs". @TrevorBarloweMD @AndrewMMoon https://journals.lww.com/ctg/abstract/9900...

EMERSE was used to identify research participants who "likely had traumatic stress based on...clinical notes in their electronic health records" in paper published in Psychiatry Research. @aghorwitz @alysonzalta https://doi.org/10.1016/j.psychres.2024.116209

Clinical data were obtained with the help of EMERSE for the paper, "Relative muscle indices and healthy reference values for sarcopenia assessment using T10 through L5 computed tomography skeletal muscle area". https://www.nature.com/articles/s41598-024-71613-x

EMERSE Community Meeting, Tuesday October 1, 2024, 1-2 PM ET. Topic: Version 7 release, with embedded natural language processing (NLP) and other new features/capabilities. Open to everyone. Register here: https://docs.google.com/forms/d/e/1FAIpQL...

EMERSE supported "Allostatic Load/Chronic Stress and Cardiovascular Outcomes in Patients Diagnosed With Breast, Lung, or Colorectal Cancer" @nickolastab @MBittencourtMD @Real_DRJXM @NeNe_LaShaun @sdent_duke @amibanerjee1 @DSadlerMD @AnaBaracCardio @Montero_MD @avirupguha https://doi.org/10.1161/JAHA.123.033295

"next generation sequencing results, disease characteristics, and treatment data were collected" with the help of EMERSE in the paper "PARP inhibitor therapy in patients with IDH1 mutated cholangiocarcinoma" @ArathiMohan3 https://doi.org/10.1093/oncolo/oyae163

"For cohort discovery, EMERSE...was employed to search the University of Michigan electronic medical record (MiChart) for eligible subjects with quiescent inflammatory bowel disease..." @MehwishAhmedMD @KaraJencks @IBDimmunology @ibddoctor @umfoodoc https://onlinelibrary.wiley.com/doi/10.1...

EMERSE was used to screen for patients with TANGO2 deficiency disorder (TDD) and 22q11.2 deletion syndrome, and was able to successfully identify a patient with both. @Sarahelegans @NotoriousEMG https://doi.org/10.1002/ajmg.a.63778

EMERSE was used to support the research for the PhD thesis "Prescription Medications and Abnormal Heart Rhythms: Understanding Genetics of Drug-Induced Long QT Syndrome" by Ana I. Lopez Medin @Ana04524295 https://dx.doi.org/10.7302/23094

Researchers at UCSF recently published a paper that used EMERSE to identify patients with metastatic breast cancer [MBC] and leptomeningeal disease [LMD]. Conclusion: "Novel therapeutic strategies for LMD remain an area of unmet clinical need." @laura_huppert @hoperugo @BalassanianRon https://link.springer.com/article/10.10...

In paper about Birt-Hogg-Dubé Syndrome in patients with Trichodiscoma and Fibrofolliculoma skin lesions, "Study patients were identified...[with] EMERSE...using the terms 'trichodiscoma' and 'fibrofolliculoma,' and iterations thereof, accounting for potential misspelling (e.g., 'trichidiscoma')" @ShabetChristina @meerkat_413 @tobi_else https://link.springer.com/article/10.1...

Clinical information (primary diagnosis, history of [opioid use disorder], pain type and levels) was abstracted using EMERSE in paper "Rotating Palliative Care Patients From Full Agonist Opioids to Low Dose Milligram Buprenorphine". https://www.jpsmjournal.com/article/S0885-39...

EMERSE was used to identify "new onset 'paroxysmal events' concerning for seizures" in the paper "Is it a seizure? Prediction tool for seizure likelihood in children aged 1–24 months admitted for electroencephalographic monitoring of paroxysmal, rhythmic, and repetitive events" @DrMelCarrasco @NancyMc69680658 https://onlinelibrary.wiley.com/doi/10.1111/epi.18018

Researchers at Case Western Reserve University used EMERSE in the paper, "Inappropriate Ordering of Multitarget Stool DNA Tests for Colon Cancer Screening", with main finding: "providers may not be familiar with guidelines for the indicated use of mtsDNA, leading to inappropriate referrals and increased costs." @SajalKulhari https://www.jabfm.org/content/37/2/328.long

EMERSE "was used to collect concomitant medications; medical history, including smoking status, urology consult, results of cystoscopy, if done; and if a new urologic cancer was diagnosed." for paper "Unexplained hematuria in direct oral anticoagulant use: a single-center retrospective case series" @laherrel @GBarnesMD https://www.rpthjournal.org/article/S2475...

Researchers used EMERSE to identify patients impacted by incarceration for what the team described as "the first study describing ethics consultation utilization for patients impacted by incarceration". Search terms included "prison", "jail", "parole", "probation", "police", "arrest" and "warden". https://www.liebertpub.com/doi/10.1089/jchc.23.10.0083

EMERSE helped identify patients with search terms such as "rib", "cadaveric", "costal", and "rhinoplasty" for the study "Outcomes of Autologous Versus Irradiated Homologous Costal Cartilage Graft in Rhinoplasty" which provided a "contemporary evaluation of outcomes in septorhinoplasty with costal cartilage." https://www.liebertpub.com/doi/10.1089/fpsam.2023.0334

EMERSE was used to identify grossly bloody stools in clinical notes for the study "Management of Hematochezia in Infants with Congenital Heart Disease Admitted to the Acute Care Cardiology Unit: A Multicenter Retrospective Pilot Study". https://www.jpeds.com/article/S002...

Researchers used EMERSE to search through clinical notes for what they report is the "largest study that investigated the association of candidate genetic variants with the risk of diLQTS [Drug-induced long QT syndrome]." https://www.futuremedicine.com/doi/10.2...

EMERSE was used to identify patients who underwent whole-spine radiography for the study, "Development and validation of an artificial intelligence model to accurately predict spinopelvic parameters" https://thejns.org/spine/vie...

Rate of preoperative hypothyroidism and thyroid hormone replacement were collected using EMERSE for the study, "Association of preoperative thyroid hormone replacement with perioperative complications after major abdominal surgery". Main findings: "Preoperative thyroid hormone replacement independently predicts operative morbidity and length of stay following major abdominal surgery." https://www.americanjournalofsurger...

EMERSE was used to identify 11 patients among 2.7 million for inclusion in a study reported to be the "largest case series of patients with long-term follow-up" for those with Le Fort III Osteotomies for Midface Advancement in the paper, "Advantages of an Image-Guided Subcranial Technique for Le Fort III Osteotomies for Midface Advancement: A Case Series" https://journals.sagepub.com/doi/10.1...

Join us on May 15 for our next EMERSE Community meeting. Featured guest speaker is Jackie Gravitt who will give a short talk on "Implementing EMERSE at the University of Virginia: Lessons Learned". https://project-emerse.org/community.html

EMERSE, "coupled with a thorough medical chart review, was used to ensure acute pathology only" in a study on Acute type A intramural hematomas. Conclusions: "Conclusions: Acute type A IMH could be treated with emergency open aortic repair with excellent short- and midterm outcomes." https://www.jtcvs.org/article/S00...

Researchers used EMERSE to identify "396 women with advanced HGSC (FIGO stages 3C-4) receiving neoadjuvant chemotherapy between 2010 and 2019" for a study looking at the "radiologic–pathologic correlation of response assessment and predictors of progression". https://link.springer.com/article/10.10...

Mark your calendar for the next EMERSE Community Meeting. May 15, 2024, 12-1 PM ET. Open to everyone, on Zoom. Register at : https://docs.google.com/forms/d/e/1FAIpQLSe...

EMERSE was used to identify patients with neonatal strokes for the study, "Routine Echocardiography is not Required in Neonates with Arterial Ischemic Stroke". https://www.thieme-connect.com/produc...

Researchers used EMERSE because the "ISTH criteria are purely clinical criteria and there is no validated algorithm to help identify bleeding cases electronically" in paper about Bleeding from DOACs. https://doi.org/10.1016/j.rpth.2023.102285

EMERSE was used to abstract data including demographics, treatment indication, topical 5-FU regimen, and toxicities in the paper "Risk of Toxicity From Topical 5- Fluorouracil Treatment in Patients Carrying DPYD Variant Alleles". https://ascpt.onlinelibrary.wile...

EMERSE was used to assist with data collection for the paper, "Pathogenic Germline Mutational Landscape in Patients With Renal Cell Carcinoma and Associated Clinicopathologic Features". https://ascopubs.org/doi/10...

EMERSE was used to "search patient records for alcohol-related keywords" to help develop a natural language processing tool that "demonstrated good discrimination of risky alcohol use using clinical text from pre-operative notes." https://doi.org/10.1111/acer...

Researchers used EMERSE to identify patients with Toxic Erythema of Chemotherapy for the "largest reported series of TEC, a difficult diagnosis given the heterogeneity of clinical presentations and histologic overlap with GVHD and other drug eruptions." https://journals.lww.com/amjdermatopa...

A team from U of Washington, UCSD, UCSF, & St. Jude used EMERSE to find patients for the abstract, "A Real-World Analysis of the Diagnostic Evaluation for Hemophagocytic Lymphohistiocytosis in a Pediatric Population" https://doi.org/10.1182/blood-2023-180086

EMERSE was used to review records of "neonates...with HIE treated with therapeutic hypothermia...admitted to the...Neonatal ICU...and followed in the neonatal developmental clinic until 24 months corrected age." https://pediatr-neonatol.com/articl...

"outcomes for consecutive breast MRIs...were retrospectively reviewed" using EMERSE. Conclusion: "High-risk screening breast MRI was effective at detecting early breast cancer and associated with favorable outcomes." https://doi.org/10.1093/jbi/wbad092

"Initial diagnoses, comorbidities and outcomes of these [osteomyelitis] patients were then manually verified...through chart review using the Electronic Medical Record Search Engine." https://drc.bmj.com/content/11/6/e003611

Researchers used EMERSE "to search inpatient and outpatient records from 2000 to 2022" in paper, "Impact of Diplopia and Ptosis From Lingering Third Nerve Palsy After Treatment of Cerebral Aneurysms" https://journals.lww.com/jneuro-ophthalm...

EMERSE was used to screen for patients with NAFLD in paper "Impact of Nonalcoholic Fatty Liver Disease (NAFLD) on Weight Loss After Bariatric Surgery". https://doi.org/10.1007/s11695-023-06865-z

EMERSE supported a review of patients with plagiocephaly and a prescription for a cranial remolding orthosis (CRO) in the paper: "Success Rates of Cranial Remolding Orthosis Treatment of Plagiocephaly Based on Initial Presentation" https://journals.lww.com/jpojournal/abs...

EMERSE was used to identify patients for a study that concluded: "Routine thromboprophylaxis during neoadjuvant chemotherapy is associated with reduced risk of VTE throughout primary treatment..." https://doi.org/10.1016/j.ygyno.2023.10.001

Use of EMERSE is described in the JMIR Research Protocols Paper, "Model Clinic to Increase Preventive Screenings Among Patients With Physical Disabilities: Protocol for a Mixed Methods Intervention Pilot Study" https://researchprotocols.org/2023/1/e50105

EMERSE supported paper from Seidman Cancer Center, "Thirty-Day Unplanned Hospital Readmissions in Patients With Cancer and the Impact of Social Determinants of Health..." https://ascopubs.org/doi/10.1200/CCI.22.00143