EMERSE (Electronic Medical Record Search Engine) is software that helps researchers accurately find and extract important patient details like diagnoses, medications, procedures, and complications from clinical notes. EMERSE is easy for non-technical people to use and enables health research that was previously inefficient or nearly impossible. As one user remarked, "The functionality is very friendly and it saved hours of time during the data collection process. Thank you."



Open source software built to commercial-grade standards
EMERSE was used to support the abstract "Risk Factors Associated with Wound Healing in Oculofacial Plastic Surgery" published online in the Michigan Journal of Medicine. https://journals.publishing.umich.edu/mjm/article/id/8870/
Patients were identified using EMERSE for the study, "Venetoclax or Pirtobrutinib in Relapsed/Refractory Waldenström Macroglobulinemia: Clinical and Molecular Predictors and Sequencing Implications", in what is reported to be the "first comparison of venetoclax and pirtobrutinib in relapsed or refractory WM" https://doi.org/10.1002/ajh.70269
Patients with a diagnosis of Pectus Carinatum (PC) and a prescription for a PC orthosis were identified with EMERSE for the publication, "Validating Clinical Anthropometry in the Assessment of Pediatric Pectus Carinatum". https://journals.lww.com/jpojournal/ab...
"All study data were collected from the electronic medical record or through electronic chart review in the Electronic Medical Record Search Engine" for the publication "The role of uridine diphosphate glucuronosyltransferase 1A4 polymorphisms on posaconazole exposure". https://journals.lww.com/jpharmacogenetics/ab...
EMERSE is proposed to be used the protocol published in JMIR: "Real-Time Type 1 Diabetes Self-Management Decision-Making in Adolescents: Protocol for a Longitudinal Mixed Methods Study Using Text Messaging and Continuous Glucose Monitoring" https://www.researchprotocols.org/2026/1/e83218
EMERSE was used to identify patients for the study, "Implantable Pulse Generator Site Pain Following Spinal Cord Stimulation: A Case-Control Study" https://journals.lww.com/onsonline/abstract/9900/im...
"Keywords including MSH2, MSH6, MLH1, PMS2, Lynch, and urothelial were queried within the Electronic Medical Record Search Engine (EMERSE) system" for the paper, "Germline Variants in Bladder and Upper Tract Urothelial Cancers: Prevalence and Clinical Context in a Large Testing Registry" https://doi.org/10.1016/j.euros.2026.02.010
"EMERSE was searched for patients with a TGNC identifier...and a GU/GYN cancer diagnosis, yielding 172 patients" for the study, "Experiences of Transgender and Gender-Nonconforming Patients With Genitourinary and Gynecologic Cancers: A Qualitative Study". https://ascopubs.org/doi/10.1200/OP-25-00677
EMERSE was used to identify cases involving child protective services for the paper "Disparities in Pediatric Admissions for Growth Faltering" https://doi.org/10.1542/hpeds.2025-008753
"Patients with likely intentional weight loss were excluded by analyzing free-text notes in EMERSE" by researchers at Case Western Reserve University for the paper "Best Practices for Diagnostic Evaluation of Unintentional Weight Loss" https://journals.lww.com/ajmqonline/abstract/202...
EMERSE was used to identify cases of Merkel cell carcinoma (MCC) with microsatellitosis for the abstract "Adverse Outcome in Merkel Cell Carcinoma with Microsatellitosis - A Clinicopathologic Study Of 25 Cases", presented at the 115th US and Canadian Academy of Pathology (USCAP) Annual Meeting in San Antonio, TX, March 2026. https://www.laboratoryinvestigation.org/arti...
"Patients were identified using search terms describing the clinical manifestations of BHDS, adrenal tumors, as well as iterations thereof using EMERSE" in the paper "Adrenocortical carcinoma as a manifestation of Birt-Hogg-Dubé syndrome" https://doi.org/10.1530/ERC-25-0285
EMERSE was used to identify patients with inflammatory bowel diseases (IBD) for a survey study conducted in Cleveland, OH. The main findings were that "insurance issues and access to infusion centers are the most frequently cited barriers to optimized IBD care." https://journals.lww.com/10.14309/01.ajg.00...
EMERSE was used in the study, "Clinical ethics consultation for patients with eating disorders: a single center retrospective content analysis". According to the study, "EC [ethics consult] was requested for 0.002% of patients impacted by ED [eating disorder] across the institution, representing 3% of total EC volume during this period...", raising concerns that "EC is underutilized within subsets of the ED population..." https://doi.org/10.1080/10640266.2026.2616487
EMERSE was used to support the research in "Understanding and Assessing Health-Related Quality of Life in Caregivers of Individuals with Traumatic Brain Injury and Comorbid Posttraumatic Stress Disorder" https://www.archives-pmr.org/article/S0003-9993...
Search criteria with EMERSE included "patients with a diagnosis of plagiocephaly, deformational plagio cephaly, nonsynostotic plagiocephaly, or positional plagiocephaly and a prescription for a CRO" for a study recently published by a team of researchers from the University of Michigan and University of Delaware. Conclusion: "Current treatment durations for infants with moderate plagiocephaly may be longer than necessary. Estimated treatment time lines should be based on the initial severity of the infant’s deformity." https://journals.lww.com/poijournal/abstract/2025...
"Patients were identified using the University of Michigan EMERSE database" for the research abstract entitled, "Single center retrospective evaluation of CHOP-based regimens in older patients with treatment naive blastic plasmacytoid dendritic cell neoplasm" which was presented at the 67th ASH Annual Meeting. https://doi.org/10.1182/blood-2025-6974
EMERSE was used in the study, "Postparathyroidectomy Bone Density Changes in Patients With Biochemically Mild Primary Hyperparathyroidism". Main conclusion: "These findings underscore the potential for tailored interventions in managing bone health in patients with mild primary hyperparathyroidism, emphasizing the need for personalized approaches to optimize outcomes." https://doi.org/10.1016/j.eprac.202...
EMERSE was used to identify participants in assisted living for recruitment in a research study. The authors noted that "study participants in long-term care settings is challenging..but our recruitment rate suggests that the two strategies used...were effective." https://doi.org/10.1177/073346482514...
"EMERSE was queried for the terms 'T1N0M0', 'T2N0M0', 'T1N1M0', and 'glottic cancer', 'laryngeal cancer'" according to researchers at the University of North Carolina who published "Missed Opportunities: Laryngologists and Lung Cancer Screening in Early Glottic Cancer Patients" https://doi.org/10.1002/lary.70239
EMERSE supported patient identification for the paper, "Association Between Hurley Stage and Comorbidities in Hidradenitis Suppurativa" published by researchers at University Hospitals Cleveland Medical Center and Case Western Reserve University. https://doi.org/10.1111/ijd.70144
EMERSE was used to search for patients with plagiocephaly and a prescription for a cranial remolding orthosis (CRO) in the study "Setting Expectations for Cranial Remolding Orthosis Treatment of Deformational Plagiocephaly Based on Changing Rates of Cranial Vault Asymmetry Correction". Main finding: " The period of greatest cranial vault asymmetry correction is the first 12 weeks of treatment, after which correction continues at a significantly slower rate." https://www.ovid.com/jnls/jpojournal/fulltext/10.109...
Use of EMERSE was mentioned in the conference paper "AI-Driven Multimodal TMJ Patient Modeling: From Unstructured Notes to Precision Treatment", presented at the Workshop on Clinical Image-Based Procedures. https://doi.org/10.1007/978-3-032-05479-1_5
Researchers at Case Western Reserve University School of Medicine used EMERSE to identify patients for the study "Vestibular Symptoms After Cochlear Implantation in Patients With Meniere Disease" https://journals.lww.com/onojournal/fullte...
EMERSE supported the research published in "Understanding the relationship between patient-reported outcome measures, clinician-rated assessments, and performance-based measures (cognitive tests and device-based estimates) of symptoms and functioning in people with Huntington's disease" https://doi.org/10.1177/18796397251366313
A retrospective chart review was conducted with the support of EMERSE for the study, "Treatment Burden in the Long-Term Management of Patients with Arteriovenous Malformation: A 15-Year Clinical Experience" https://doi.org/10.1177/27325016251377060
EMERSE was used to support the work for the PhD thesis by Jennylee Swallow, "Provider Documentation and Patient/ Parent-Reported Social Needs for Children Living with Sickle Cell Disease: Implications for Quality, Completeness, and Utility of Social Needs Data to Support a Learning Health System". https://dx.doi.org/10.7302/26930
"Clinical characteristics were abstracted from medical records using the Electronic Medical Record Search Engine (EMERSE)" in a study on the "Polysomnographic diagnosis of obstructive sleep apnea in children with cerebral palsy" https://doi.org/10.1016/j.ijporl.2025.112512
In the study, "Mycoplasma pneumoniae-Induced Rash and Mucositis: Clinicopathologic Characterization of 11 Cases" cases were identified with the help of EMERSE by searching for "Mycoplasma pneumoniae-induced rash and mucositis", "MIRM", "reactive infectious mucocutaneous eruption", and "RIME". https://onlinelibrary.wiley.com/doi/10.1111/cup.70028
EMERSE was used to identify patients with pectus carinatum who were given a prescription for pectus carinatum orthosis (PCO) for the study, "Effect of Orthosis Daily Wear Time on Pectus Carinatum Treatment Outcomes". Main finding: "Average daily wear time significantly impacts outcomes in pectus carinatum orthotic treatment." https://journals.lww.com/jpojournal/abstract/990...
EMERSE was used to support the work of Peijin Han for her PhD thesis entitled, "Computational Algorithms for Identifying Patients Living with Dementia in Healthcare Systems". https://dx.doi.org/10.7302/27061
EMERSE was used for the abstract, "Computable Phenotype for Identifying Patients with CHARGE Syndrome: Opportunities to Improve Research and Care Coordination", presented a the APHA [American Public Health Association] 2025 Annual Meeting and Expo.
Participant recruitment was support with EMERSE for an mHealth study that examined compliance rates among partners of individuals with traumatic brain injuries. https://mhealth.jmir.org/2025/1/e73772
Athletes with initial and repeat concussions were examined for time to recovery in a study supported by EMERSE. Primary finding was "no differences in time to recovery between initial and repeat concussions sustained by the same athlete." https://journals.lww.com/cjsportsmed/abstract/2025/0...
EMERSE was used to support the study "Cognitive impairment is associated with poor diabetic foot ulcer outcomes". https://www.primary-care-diabetes.com/article/S17...
EMERSE was used to identify patients with a diagnosis of granulomatosis with polyangiitis (GPA)- related subglottic stenosis (SGS) in the study, "C- Reactive Protein Serum Values in Idiopathic and Autoimmune Subglottic Stenosis" https://onlinelibrary.wiley.com/doi/10.1002/lary.70167
"EMERSE was searched for side effects, including nausea, diarrhea, vomiting, neutropenia, and fatigue" in a study that "finds evidence that patients with CES1 rs3785161 AA and ABCG2 rs2231142 AA/AC genotypes had higher rates of severe toxicity and neutropenia, respectively, during irinotecan therapy." https://journals.lww.com/jpharmacogenetics/abstract/2025/100...
EMERSE "was used to identify eligible patients" for the study "Hypocalcemia After Cervical Procedures in Patients with a History of Nonbariatric Gastrojejunostomy" https://link.springer.com/article/10.1245/s10434-02...
EMERSE was used in the study, "Clinical and demographic characteristics of adolescents, emerging adults, and young adults presenting to an emergency department following a suicide attempt" @BrdarNM https://acamh.onlinelibrary.wiley.com/doi/10.1002/jc...
EMERSE was used to search for terms describing delirium behaviors such as "mental status changes, altered mental status, hallucinations, agitation, disorientation, lethargy, and inattention" for a study conducted at the U of Michigan School of Nursing.
https://connect.springerpub.com/content/sgrjdnp/18/1/68
Researchers at UCSF used EMERSE in the abstract "Evaluation of Presenting Symptoms in Pediatric Patients with Hemophagocytic Lymphohistiocytosis (HLH) Versus HLH Mimics" presented at the 2025 Clinical Immunology Society (CIS) Annual Meeting.
@mattzinter_MD
https://doi.org/10.70962/CIS2025abstract.172
EMERSE was used by researchers at UNC-Chapel Hill for the abstract "Immunomodulator Use in Steroid Refractory Immune Checkpoint Inhibitor Pneumonitis" presented at the ATS International Conference in San Francisco.
https://doi.org/10.1164/ajrccm.2025.211.Abstracts.A5509
"...a manual search confirmed all diagnoses and fractures....with the assistance of an internally developed software...EMERSE..." in paper about fractures in adults w/ intellectual disabilities and autism.
@MichelleSCaird
https://doi.org/10.1111/jir.13255
Researchers "searched the Department of Pathology archives and EMERSE...for BIMTs that had undergone single-nucleotide polymorphism (SNP) microarray testing" for paper on BAP1-inactivated melanocytic tumours.
@ZoumberosMD @skinandsoftbits @DoruAndea
https://doi.org/10.1111/his.15434
EMERSE was used to "identify GMFCS [gross motor function classification system] as close to day 0 as possible" for the study "Prognostic comparison between GMFCS and WCI for 5-year risks of 22 relevant health outcomes for adults with cerebral palsy: Expanding the methodological menu for prognostic model research"
https://www.sciencedirect.com/science/article/abs/pii/S193....
Clinical notes were searched...using [EMERSE] and key search terms included 'atrial fibrillation', 'atrial flutter', 'arrhythmia', 'tachycardia', and 'hypertension'" for the paper "Pharmacogenetic associations of GATA4 and KCNQ1 with ibrutinib cardiovascular toxicity"
https://journals.lww.com/jpharmacogenetics/abstract/2025...
"TriNetx..and EMERSE...was used to identify patients who satisfied the inclusion criteria, with the assistance of UC's Center for Health Informatics" for the paper, "Outcomes and Prognostic Assessment of Post-Transplant Lymphoproliferative Disorder: 20-Year Experience"
@hiragss @OmerZulfa @TMaggeMD @shimulshah73 @TahLatif
https://doi.org/10.3390/lymphatics3010005
EMERSE supported recruitment for the study, "Improving Outcomes for Care Partners of Individuals With Traumatic Brain Injury: Results for a mHealth Randomized Control Trial of the CareQOL App"
@Srijan_SenMDPhD @ZhenkeWu
https://www.archives-pmr.org/article/S0003-9993...
EMERSE was used "to capture additional patients...with SMI [serious mental illness] whose medical record may contain out of date or incorrectICD diagnosis codes..." which "yielded 33 additional patients".
"one of the strengths of this study was the utilization of EMERSE."
@jnatediehl @AudreyLKhoury @julia_brickey @gitamody @BenHaithcockMD
https://jtd.amegroups.org/article/view/94795/html
"...chart review of all infants born during the training period was performed using a web-based tool called...EMERSE".
Main finding: "hands-on training with the MiHip simulator improved resident knowledge and DDH examination confidence, and ultimately, improved diagnostic accuracy in the clinical setting."
@SaumyaG @_KrupaPatel_ @meduc8r
https://www.sciencedirect.com/science/article/abs/pi...
Data extraction was supported with EMERSE for the paper, "Documenting Pediatric Delirium During Transitions of Care: A Single Site Observational Study" https://journals.sagepub.com/doi/10.1177/08...
EMERSE was used to support the study "Development and acceptability testing of a tracheostomy decision support video for parents"
@stephaneonatal @KenPituch
Paper at: https://www.sciencedirect.com/science/article/pii/S2...
Video at: https://deepblue.lib.umich.edu/handle/2027.42/192788
"EMERSE...software was used to find LI [legacy interventions] in the medical records as well as manual chart review" for abstract, "Delivery of Legacy Interventions at C. S. Mott Children’s Hospital QI Study" presented at the 2025 Annual Assembly of Hospice and Palliative Care https://www.jpsmjournal.com/article/S0885...
"...strengths of this study include the use of EMERSE to identify eligible patients..." in the paper, "Clinical Delivery of Whole Systems Traditional Chinese Medicine and Impacts Upon Patient Reported Outcomes During IVF". https://doi.org/10.1177/27536130251349116
"The EMR and local registries of patients at the University of Michigan were searched using...the EMERSE software" as reported in the abstract "Clinical and genetic characteristics of patients with adrenocortical carcinoma and lynch syndrome" @DrGaryHammer https://www.endocrine-abstracts.org/ea/0107/ea01...
EMERSE was used to identify patients for the paper, "Brain MRI Lesions in Alexia Without Agraphia: A Case–Control Study", the "first controlled study with MRI data to show imaging support for both hypothesized mechanisms of AWA." @JerShapi https://journals.lww.com/jneuro-ophthal...
Patients with peripartum cardiomyopathy (PPCM) were identified with EMERSE for the study "Efficacy and Safety of Implantable Cardioverter-Defibrillator Use in Peripartum Cardiomyopathy" @AngMNoll @AurasAtreya @JasneetDevgun @MGhannamMD @MelindaDavisMD https://www.sciencedirect.com/science...
Slides and video recording of the recent EMERSE Community meeting from May 14, 2025 are now available online at https://project-emerse.org/community.html, which included a great presentation by Erik Harden from Columbia University Medical Center.
Researchers at Utrecht University in the Netherlands used EMERSE to identify 21 patients with Boerhaave syndrome, "a rare, life-threatening condition, characterized by spontaneous esophageal rupture" https://link.springer.com/article/10.1007/s00464...
EMERSE "was utilized to perform term-based queries of clinicians' notes" for study "Factors Associated With the Recovery of Left Ventricular Ejection Fraction in Patients With Anthracycline-Induced Left Ventricular Dysfunction" @ShuggTyler @rtdess @salimhayek @JasmineLuzum https://journals.sagepub.com/doi/fu...
Join us for our next EMERSE Community Meeting. Open to everyone, Virtual online. Monday February 10, 2025, 1-2 PM ET. Topic: Updates from the EMERSE team. Register at: https://bit.ly/emerse-community-feb-2025
Researchers used EMERSE for a "retrospective analysis of all patients undergoing superficial parotidectomy for biopsy-confirmed benign parotid gland tumors over a five-year period." @Jossmi23 @MattSpector4 https://www.sciencedirect.com/science/article/pii/S01960...
EMERSE helped "screen clinical notes...to ensure compliance with exclusion criteria" in study of the "first independent investigation validating the diLQTS PRS ...within a large real-world patient cohort." @Ana04524295 @JasmineLuzum https://journals.lww.com/jpharmacogenetics/abstract/2025/01...
EMERSE was used for the study, "Diabetic foot infection severity as a predictor of re-ulceration following partial forefoot amputation". Finding: " Patients with higher diabetic foot infection severity based on IDSA classification are at greater risk for developing re-ulceration following a partial forefoot amputation." https://www.jfas.org/article/S1067-2516(24)00277-1/abstract
Join us for our next EMERSE Community Meeting. Open to everyone, Virtual online. Monday February 10, 2025, 1-2 PM ET. Topic: Updates from the EMERSE team. Register at: https://bit.ly/emerse-community-feb-2025
EMERSE supported the research: "Documenting human papillomavirus vaccine refusal among adolescents in electronic health records: A mixed methods study" @stjeandenise https://www.sciencedirect.com/science/article/abs/pii/S0264410X24011496
Researchers used EMERSE for the "first study to assess the prevalence of patient-provider discussions regarding LAAO [left atrial appendage occlusion] procedures in patients following a major bleed while on anticoagulation." @GBarnesMD https://www.thrombosisresearch.com/article/S0049-3848%282...
NCI Cancer Data Science
@NCIDataSci
Learn more about Electronic Medical Record Search Engine, a text processing system that uses natural language processing capabilities to help you work with unstructured data from electronic health record systems.
https://datascience.cancer.gov/news-events/even...
Jill Barnholtz-Sloan, Ph.D.
@NCIJBSloan
The first event of the #CCDI webinar series this year discusses @projectEMERSE, an open-source software supporting #CancerResearch using clinical notes from EHRs:
https://datascience.cancer.gov/news-events/even...